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The theory hypothesizes that aging is associated with structural impairment caused due to the accumulation of oxidative damage to crucial macromolecules (lipids, DNA, RNA, and proteins) brought about ROS and RNS (Liguori et al., 2018)

These agents have been used since the 1950s for psychotic disorders such as mood disorders and schizophrenia with the development of chlorpromazine as the first anti-psychotic (78)

The chromosomes in a patient showing both mongolism and the Klinefelter syndrome

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