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Impact of Changes in Free Concentrations and Drug-Protein Binding on Drug Dosing Regimens in Special Populations and Disease States

Funding This study was supported by a Commercial Development & Industry Partnership (CDIP) grant (CT20584-University of Sydney and Whiteley Corporation) and a Department of Industry, Innovation and Science (Innovative Manufacturing CRC Ltd.) and Whiteley Corporation co-funded project grant A Novel Approach to Biofilm Disruption and Removal (IMCRC/WLY/08052019.1)

The rate constant for the fusion construct with dithiol PfGrx C88S was about three times smaller and decreased again fivefold for monothiol PfGrx C32S/C88S (Fig

All recorded locomotion data were analyzed and calculated using LABORAS 2.6 software (Metris B.V.)

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Acad Emerg Med