l carnitine deficiency causes Brain nonsyndromic autism with an extreme male bias: A hypothesis - Beaudet - 2017 - BioEssays Mechanism of L-carnitine deficiency in
Description
doi: 10.1038/s41591-018-0128-1
From 1.5 g ALCAR twice daily (23 patients, plasma levels from 15 patients obtained), the treatment was changed to once daily doses of 1g (4 patients), 2g (7 patients), or 3g (12 patients), respectively
For example, carnitine-modified drugs can effectively target OCTN2 transporters to improve drug bioavailability [182, 183]
Authors' contributions The authors' responsibilities were as follows--QG and JLF conceived and researched the review
Without enough L-carnitine, fewer fatty acids get into the mitochondria, and more fat gets stored instead of burned
