glutathione pyridyl disulfide reductase It favors its accumulation in the regions of high electron flux in cells where reactive species are generated. Glutathione disulfide - Wikipedia

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Cha and co-authors showed that Grx3 has a role in cardiomyocyte regulates contractility and cardiac hypertrophy and cardiomyocytes with heterozygous deletion of Grx3 (Grx3+/-) showed a decrease in Ca 2+ sensitivity in cardiomyocyte filaments

This prediction is supported by experimental evidence suggesting that pharmacological and genetic perturbation of polyamine metabolism promotes Treg cell differentiation at the expense of Th17 cells [243]

doi:10.1016/0092-8674(75)90180-4

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For bio-distribution test, fluorescence intensity of each organ was normalized to the cardiac fluorescence values of the corresponding control group