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Efficacy and limitations of senolysis in atherosclerosis

Receptor for the C3a anaphylatoxin is expressed by neurons and glial cells

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Simultaneously, released Cu 2+ causes redox reaction with the intracellular overexpressed GSH, and subsequently produces Cu + for initiation of Fenton-like reactions, resulting in the production of OH and robust anticancer therapy

Superoxide and DHA are therefore the most likely of the molecules shown in Table 1 to contribute to uncatalyzed production of GSSG in vivo