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These preparations can contain substantially higher and less predictable concentrations of mitragynine and 7-hydroxymitragynine, resulting in exposure profiles that differ markedly from traditional use [3, 4]

Pregnancy and breastfeeding: Use only if recommended by a healthcare provider

So to fill a vial with 3 mL, you draw and add three full syringes (300 units total)

Rather than being limited to one specific area of research, it has become associated with studies spanning tissue biology, cellular communication, vascular biology and extracellular matrix research

It is distinct from sterile water for injection (SWFI), which contains no preservative and is single-use only

Human data is still very limited, including small pilot work such as the knee pain survey of 16 patients, plus a few other early studies and reviews calling out the lack of large, rigorous trials