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Evidence suggests that the cellular redox state plays a role in regulating neuronal activity and clock gene transcription in the suprachiasmatic nucleus (SCN)

Additionally, the increased levels of citrate in the cytoplasm activate the key regulatory enzyme of fatty acid biosynthesis, acetyl-CoA carboxylase (ACC) while at the same time citrate allosterically inhibits the rate-limiting enzyme of glycolysis, PFK-1

doi: 10.1080/08860220601095827

MIND not Mediterranean diet related to 12-year incidence of cognitive impairment in an Australian longitudinal cohort study

Integrating Multiple Layers of Genomic Data to Identify Regulatory Programs of Gene Expression in KRAS Mutant Rectal Cancers

References 1 Abu-RubM.MillerR