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In the presence of ADP, protons flow down their thermodynamic gradient from the inner membrane space of the mitochondrion back into the mitochondrial matrix

The AhR agonists and inhibitors currently used in in cancer therapy include aminoflavone, ITE and SR1 (10,11,14,105)

Unlike acute wounds, which follow a well-defined healing cascade of re-epithelialization, fibroblast proliferation, and angiogenesis, chronic wounds remain trapped in a prolonged inflammatory phase characterized by microbial persistence and dysregulated immune responses [4,5,6]

Typical symptoms of chloride loss include dehydration, fatigue, shortness of breath, confusion, nausea, and vomiting (336)

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Blandini F, Fancellu R, Martignoni E, Mangiagalli A, Pacchetti C, Samuele A, Nappi G