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doi: 10.1038/nrrheum.2017.37 6 YangLChuZLiuMZouQLiJLiuQet al

2) and this feature is very important for analysis the primary structure of proteins, for effects on changes in secondary structure and for stabilization tertiary and quaternary structure

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Meanwhile, tryptophan 2,3-dioxygenase (TDO2), the rate-limiting enzyme of the kynurenine pathway, was found to be upregulated in ovarian cancer tissues, which promotes tumor cell proliferation, migration and invasion (113)

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These transcripts are tissue-specific, have different functional consequences but no recognizable polyadenylation signal in their 3UTRs, and they are tissue-specific