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347 After the development of first-generation SERMs tamoxifen and second-generation SERMs toremifene and raloxifene, several novel endocrine therapy drugs are currently under development to enhance efficacy and reduce toxicity

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Sulforaphane stands out as a highly studied and promising therapeutic agent currently undergoing preclinical and clinical evaluation of a multitude of diseases and disorders (7)

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Folate dietary insufficiency and folic acid supplementation similarly impair metabolism and compromise hematopoiesis