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Goodman and Gilmans The Pharmacological Basis of Therapeutics, 10th Edition, Chapter 58

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However, the mechanism by which cells located far from the wound sense tissue damage and establish a persisting memory is still unknown

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Because GHK-Cu's anti-inflammatory action is selective rather than broadly suppressive, it calms rosacea-prone and reactive skin without the barrier-thinning tradeoffs of steroid-based approaches

TAF does not seems to be impacted thanks to a faster internalization in target cells (159, 160)