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Use a syringe with clear ml markings for the reconstitution step, not an insulin syringe

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Why B12 Shots are Better than Oral Supplements Jul 2, 2025 5 min read Vitamin B12 is essential for many vital bodily functions including red blood cell production, nerve health, and DNA synthesis

If oral B12 replacement has been trialled in a person with metformin-associated B12 deficiency, I would suggest that a repeat measurement of B12 levels after 812 weeks is a good time to reassess whether absorption is adequate or whether a switch to intramuscular replacement is required

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