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Notably, TMAO also amplifies ERS markers such as heat shock protein 60 and glucose regulated protein 78kD in macrophages, correlating with elevated toll-like receptor 4 expression and proinflammatory cytokine production (e.g., TNF-, IL-6) (88, 89)

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Despite increased public education and government policies to ban smoking in public places (Balmford et al., Autophagy removes damaged or junk organelles in cells (Ashrafi and Schwarz, Furthermore, as SE offspring have reduced brain antioxidants and increased cellular oxidative damage (Chan et al., Materials and Methods Animals The animal experiments were approved by the Animal Care and Ethics Committee at the University of Technology Sydney (ACEC#2011-313A)