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In all the vertebrates examined, cholesterol serves as the precursor for bile acid biosynthesis, whereby a water- insoluble, hydrophobic membrane lipid is converted into water-soluble derivatives that can be excreted in bile

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D., Wei X., CardenasNavia I., et al., Exon Capture Analysis of G ProteinCoupled Receptors Identifies Activating Mutations in GRM3 in Melanoma, Nature Genetics 43, no

59 HuangW.LeeM.LeeC.NgK.HsuY.TsaiT.et al (2019)