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Description
IGF-1 expressing microglia are induced by cytokines released from T helper 2 cells, which may be neuroprotective, promoting neurogenesis

Rahmattulla et al

Crosstalk between cytoplasmic RIG-I and STING sensing pathways
N Engl J Med

A secondary prevention is done for individuals displaying multiple islet autoantibodies, with the aim of stopping autoimmune processes and potentially preventing the clinical manifestation of diabetes
This matters for people whose bodies struggle to absorb B12 through food, since an injection skips the digestive absorption step that oral supplements depend on