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A recent study reported that Hmox1 activation induces heme accumulation and drives cardiomyopathy through ferroptosis induction, whereas inhibition of Hmox1 reduced cardiac damage in SCD 46

Researchers should approach dosing with appropriate caution and ideally work with knowledgeable healthcare providers

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What are the long-term effects and risks of antioxidant therapies

For some patients, IM therapy may provide an effective alternative to oral supplements and a more accessible complement to IV therapy

Written informed consent was obtained from all participants before entry into the study