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Curr Opin Rheumatol 31:517524

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A phase 1, randomized, single-ascending-dose study to investigate the safety, tolerability, and pharmacokinetics of DSTA4637S, an anti-staphylococcus aureus thiomab antibody-antibiotic conjugate, in healthy volunteers

Lactose-appended -CD successfully increased delivery of the model drug into the mouse brain [163]
