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Description
It's mechanism-driven protocol design

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Isoliquiritigenin (ISL), a type of flavonoid, has many health benefits but has poor bioavailability and stability and limits its application in clinical studies

doi: 10.1097/MCG.0b013e31826ae849 12 WeberCRTurnerJR

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The most-cited animal work is a series of long-term experiments in CBA mice and Wistar rats reporting that pulsed administration of Epitalon increased mean and maximum lifespan, reduced the incidence of spontaneous tumour formation, and preserved oestrous cyclicity in females past the age at which controls became acyclic
