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10.1111/nyas.12069 Ann

The researchers employed a Quadratic Unbounded Binary Optimization (QUBO) model that runs on a quantum-inspired device to search for compounds similar to remdesivir

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doi: 10.1038/s41557-019-0317-7 84 XieYXieFZhouXZhangLYangBHuangJet al

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Importantly, a negative control mutant version of Strep-Gid4 (lacking C-terminal residues required for binding Gid5 in the scaffold module) failed to associate with any GID SR4 or Gid12-bound GID SR4 subunits