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These compounds work through entirely different mechanisms, making direct comparison difficult

For example, a 2013 trial found it significantly improved menopause symptoms across multiple categories, including vasomotor, physical, and psychological measures.62 While its primarily studied for menopause, theres some evidence suggesting it may also help with PMS-related discomfort.53 Chasteberry (Vitex) Pycnogenol In a 2011 study, perimenopausal women who took Pycnogenol for two months experienced statistically significant reductions in hot flashes, night sweats, mood swings, irregular periods, reduced libido, and vaginal dryness.9 For PMS symptoms, a 2008 study found Pycnogenol significantly lowered menstrual pain in those with dysmenorrhea.63 Wild yam Wild yam has a long history of traditional use for menopausal and inflammatory symptoms

It signals your brain that you are full

Legal Status in Australia In Australia, BPC-157/TB-500 blends are not approved for human therapeutic use

But that said, endo can potentially: Alter ovarian function Increase inflammation around the ovaries Cause ovarian cysts (called endometriomas) Disrupt follicle development in some cases This doesn't mean that ovulation always stops when you have endo, but it can become more painful, less predictable, or associated with fertility challenges for some people