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Based on evidence, synbiotics may confer their hypotriglyceridemic effects through impeding triglyceride absorption from the gut, via stimulating GLP-1 levels (75), stimulating the secretion of FIAF, by which inhibiting endothelial LPL, which may lead to decreased release of triglycerides from circulating chylomicrons and very-low-density lipoprotein (VLDL) (76), and lowering TG levels through reducing hepatic de novo lipogenesis, induced by carbohydrate-responsive element-binding protein (ChREBP) and sterol regulatory element-binding protein (SREBP) (76)

J Stat Softw

192 LafourcadeM.LarrieuT.MatoS.DuffaudA.SepersM.MatiasI.et al (2011)

10.1016/j.heliyon.2024.e40003 87 HeY.LiY.LaoQ.QinT.XieX.JiangW