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In their systematic review and meta-analysis, Finnerup et al

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Gut microbiota metabolite trimethylamine N-oxide promoted NAFLD progression by exacerbating intestinal barrier disruption and intrahepatic cellular imbalance

Instead of an aldolase with strict HTML specificity, serine hydroxymethyltransferases (SHMT) (Strijbis et al., 2009

This activity establishes a net charge across the plasma membrane with the interior of the cell being negatively charged with respect to the exterior

doi: 10.1006/nimg.2001.1011 [DOI] [PubMed] [Google Scholar] 51.Tahedl M, Levine SM, Greenlee MW, Weissert R, Schwarzbach JV