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Biomolecules 13:1398

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PubMed Central, Meyerhoff, Dieter J., et al

First, the Protein Data Bank ( was used to download the SIRT1 crystal structure ( PDB code: 4ZZJ )

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SBS17, induced by 5-fluorouracil and an unknown endogenous driver 42 , and SBS18, caused by the mutagenic bypass of 8oxo-guanine, a lesion linked to reactive oxygen species 14 (Fig
