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Here is a condensed recap of where each compound currently stands: CJC-1295: not FDA-approved

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THE FUTURE OF NAD+ IN CLINICAL PRACTICE Until recently, antiaging therapies were limited to repairing the consequences of aging, but now there is clear evidence that aging can be targeted from its root cellular cause giving the opportunity to slow and even reverse aspects of aging

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Due to the feasibility, we focused on CPs caused by mutations in epigenetic writers, which constitute the biggest group of CPs and have been most characterized in terms of immunopathology ( Figure 1 ) ( Figure 1 2 Methods 2.1 Registration This systematic review was registered in the INPLASY database (registration number: INPLASY2025120066) and is reported in accordance with PRISMA 2020 guidelines

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which factors define the response to treatment

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