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Discussion Significance of the study To our knowledge, this is the most comprehensive network meta-analysis comparing the efficacy of SL, IM, and oral routes of administration of vitamin B12 in patients with vitamin B12 deficiency

That's why the Office of Dietary Supplements states that people over 50 should gain most of their B12 from dietary supplements or fortified foods

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It may influence cellular methylation balance, metabolic signaling, and NAD-related biochemical pathways

Always consult with a qualified healthcare provider for any medical concerns or questions you may have.

For example, when a fieldworker has measured the weight and length of a child, a supervisor or scientist will undertake the same measurement and compare their findings with that of the fieldworker