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Cancer cells were sensitive to GGsTop when grown in cystine-free with GSH-supplemented conditions, but this increased sensitivity was reversed when cells were provided with cysteinylglycine, the product of GGT-mediated GSH catabolism (Fig

The results and data interpretations of the endpoint fluorescences were independently validated by electrophoretic mobility shift assays (Fig

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doi: 10.1016/j.tins.2013.10.003 26 KennedyGSpenceVAMcLarenMHillAUnderwoodCBelchJJ