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128 They determined the brain-targeting efficiency after intranasal administration of a methotrexate solution (free MTX), methotrexate-loaded ISG (MTX-ISG), methotrexate-loaded niosome (MTX-N), and MTX-N-loaded ISG (MTX-N-ISG)

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Available from: Sedatives and/or anesthetics may be used If necessary, a relaxation medication may be given through an intravenous (IV) line in the patients arm, but the patient is usually conscious during this procedure
Note that this code is used for documenting the administration event only