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Description
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Researchers should approach PE-22-28 with appropriate caution given the early stage of human evidence
PMCID: PMC8227053
Beyond the ENS, this transcriptional factor when selectively activated by the microbial metabolite indole produced by tryptophanase-expressing gut microbes interestingly induces neurogenic effects in the adult murine hippocampus as identified by elevated expression of -catenin, Neurog2, and VEGF- (Wei et al., 2021)
Environmental Protection Agency (EPA) DSSTox database using the EPA ChemReg chemical registration system to associate the chemical structures with valid identifiers such as CASRNs, DTXSIDs, and names (available in Additional file 3) [36]
They mainly interact with DCs to improve antigen presentation and maintain intestinal homeostasis
