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doi: 10.1158/1535-7163.MCT-08-1090 173 WirthnerRWrannSBalamuruganKWengerRHStiehlDP

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Folate Receptor Autoantibodies (FRAAs) in ASD A larger percentage of children with ASD have been found to have autoantibodies against the folate receptor alpha (FR) , which impair folate transport across the blood-brain barrier (BBB)

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This rapid neurotransmitter-like BDNF signaling is mediated via direct modulation of membrane channels, especially voltage-gated ion channels [106]

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