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The pathogenesis involves both innate and adaptive immune responses targeting bile duct cells and various extrahepatic tissues [241,242,243]

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The sections were treated with goat anti-Rat Alexa Fluor 488 IgG (H+L) (1:500, A-11006, Invitrogen) and DAPI (5 mg ml 1 ) for visualization

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Bee venom (BV) has traditionally been used in Chinese medicine for pain, arthritis, rheumatism, skin diseases, etc

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