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At the indicated time points after adding formaldehyde (0, 10, 20, 40, 60, 120, 240 and 360 min), a sample was taken and diluted 1:50 in extraction solvent for LCMS measurements (concentration of compounds ~50 M) or 1:10 in water for GCMS-based detection of formaldehyde (highest concentration = 125 M)

The neurotoxin 3-NP is a widely used model for studying the pathology of HD

Effects of varenicline and nicotine replacement therapy on arterial elasticity, endothelial glycocalyx and oxidative stress during a 3-month smoking cessation program

While direct evidence linking the RARA::RXRA and RARA::RXRG complexes to CCL11 expression in the CNS is currently not well established, it is plausible to speculate that retinoic acid signaling through these complexes could inhibit CCL11 expression in specific brain conditions

10.1039/b407701f 182

[DOI] [PubMed] [Google Scholar] 17.Rodriguez TE