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Because IM injections send B12 directly into muscle, the vitamin peaks in blood within about an hour, ensuring tissues get what they need

The most common reason someone would need to have their vitamin B12 levels checked is to evaluate for vitamin B12 deficiency, says Mike Ren, MD, assistant professor of family and community medicine at Baylor College of Medicine

Peter Lurie, a former FDA official who now leads the Center for Science in the Public Interest

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For someone with confirmed deficiency, exogenous GH is an option too, under real clinical oversight