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J Affect Disord 136:933939 Mahmoudi M, Bayat AH, Boroujeni ME et al (2019) Curcumin protects purkinje neurons, ameliorates motor function and reduces cerebellar atrophy in rat model of cerebellar ataxia induced by 3-AP

Gallovi, F., Valentov, , Ampuero, J

Concentration (start) Volume (start) = Concentration (final) Volume (final) Protocol [1] Monochlorobimane (mCB) is added to the second half liver tissue homogenate to a final concentration of 100 mM along with glutathione S-transferase (1 U/mL) obtained from equine liver

This programmed leptin resistance of overfed neonatal rats is age dependent: in juvenile (24 days old) rats raised in small litters, expression of LepRb is decreased by ~45% in the hypothalamus 115

Nature 562 , 538544 (2018)

These findings highlight the NLRP3 inflammasome as a viable therapeutic target with the potential to alleviate the impact of neuroinflammation in various CNS diseases