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Biochem Biophys Res Commun (1996) 229:8915.10.1006/bbrc.1996.1898 32 KashSFJohnsonRSTecottLHNoebelsJLMayfieldRDHanahanDet alEpilepsy in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase

While excessive intracellular Fe 2 can generate substantial amounts of hydroxyl radicals through the Fenton reaction, leading to oxidative stress, under physiological conditions, a balance between Fe 2 and Fe is maintained to prevent such oxidative damage

52 transcription factors were upregulated while 86 transcription factors were downregulated

This also brings up the idea of using bioengineered strains to re-ferment and condition beers that might have high thiol precursors when bottling beer (mix-fermentation wine grape beers or dry-hopped sour beers, for example)

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