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Schrauwen-Hinderling, V

Necroptosis is a cell death mechanism which is activated due to RIPK1 and RIPK3 (receptor interacting protein kinase 1 and 3) ( ROS not only affects main pathways but also hinders non-relevant pathways, such as Brahma-related gene 1 (BRG1) expression (66)

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Ferroptosis of retinal cells, such as RPE, photoreceptor, and RGC, has been reported to be involved in the progression of age-related/inherited macular degeneration, blue light-induced retinal degeneration, glaucoma, DR, and retinal damage caused by retinal ischemia-reperfusion (I/R) (Figure 1

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