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The gut microbiota plays a critical role in type 2 diabetes (T2D) pathogenesis, with T2D patients showing dysbiosis, disrupted intestinal barriers, and abnormal TMAO production and absorption (Wang et al., 2011

In an interim analysis of clinical trials, patients were assigned to receive resmetirom (80 mg or 100 mg) or a placebo

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the ALC chemical structure can be easily absorbed in the gastrointestinal tract
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