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Some people lost up to 24% of their body weight

Thus, NOX2 does not appear to be a potential source of oxidative stress in this context

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Int Immunopharmacol 17(4):11011107

Despite some reports on the similarities between senescence and eryptosis at the morphological level [67], intracellular Ca 2+ elevation [74], Ca 2+ -driven activation of Gardos channels [70], PS exposure [76], or ROS contribution [71], senescence of erythrocytes cannot be considered an RCD of these cells and should be clearly distinguished from eryptosis

Hsiang T.-Y