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Uremic toxins such as indoles are produced by the intestinal microbiota, and these toxins worsen renal function and the prognosis of end-stage renal disease [17]

Aug 1 2019;104(8):3525-3534
However, the evidence for chronic fatigue syndrome/myalgic encephalomyelitis (ME/CFS) remains limited, and NICE guideline NG206 does not recommend supplements as a treatment for ME/CFS
