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In view of the growing agricultural and industrial activity that are the main sources of Cu addition in nature, understanding the physiological and biochemical mechanisms of Cu toxicity in plants constitutes an important tool for the selection of more tolerant genotypes based on biochemical and physiological indicators to heavy metal stresses

Zhang P, Zhou C, Ren X, Jing Q, Gao Y, Yang C, et al

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Take vitamin C: oral doses over one gram result in poor absorption due to limited intestinal capacity
Vitamin D may have antithrombotic effects by reducing cytokine-induced changes in tissue factor and thrombomodulin, as suggested by several experimental studies (Ueno et al., 2019)