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However, several proposed actions are believed to underlie its physiological effects: 1

It plays a vital role in cellular migration, proliferation, and differentiation

Specifically, lactate accumulation contributes to an acidic microenvironment, which can promote the release of free iron from ferritin (ferritinophagy) or alter the function of transferrin receptors, thereby increasing the labile iron pool required for the Fenton reaction

These pathogenic events stimulate fibroblasts to proliferate and transform into myofibroblasts

Prescribers are encouraged to monitor their patients' progress and adjust treatment as necessary

Your physician will develop a personalized plan and monitor your progress through regular labs and follow-ups to optimize timing and dosing