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Figure 1 and Table 2 have been included to represent schematically IGF-1 actions in metabolism with target organs

It has been studied extensively in metabolic research, particularly around adipose tissue regulation and energy metabolism

Visceral Fat Reduction: The most dangerous fat deep abdominal visceral fat was notably reduced without changes in calorie intake

No notable impact on blood glucose, cholesterol, or blood pressure has been observed in shortterm studies (glucose tolerance findings)

Thymosin Alpha 1 is one of the safest peptides in clinical use

Additionally, it is now known that pro-inflammatory cytokines also hijack IGF-1 intracellular signalling by phosphorylating serine residues on insulin related substrate (IRS) molecules and hence impeding their binding to IGF-1R [124]