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PLoS One 10, e0139136

Its analgesic effects were comparable to that of morphine, but notably, LPF-35 did not induce tolerance or dependence, suggesting a non-opioid mechanism of actionpossibly through local anti-inflammatory effects and modulation of nociceptive signaling at nerve endings and ion channels

D.FoyerC

[DOI] [PMC free article] [PubMed] [Google Scholar] Michels L.R., Fachel F.N.S., Schuh R.S., Azambuja J.H., de Souza P.O., Gelsleichter N.E., et al

It helps keep the skin moisturized, resulting in a smoother and more youthful complexion

Contrary to CHAOS, the HOPE trial failed (Yusuf et al