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Description
Out of the top 20 gene sets enriched in each condition, 9 gene sets, including Heme metabolism and ROS pathway, were common to all 4 conditions and an additional 3 gene sets, including Cholesterol synthesis were enriched in 3 out of 4 conditions (Figure 3B, S3AB)
They used a mouse model of diet-induced obesity and combined metabolomic analyses in BAT and other tissues with stable-isotope tracer studies to answer this question
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Duration: Eight to twelve weeks
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Fjellstedt E, Denneberg T, Jeppsson JO, Tiselius HG
