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Structure of the blood-brain barrier and its role in the transport of amino acids
This overexposure pattern depletes intracellular antioxidants, disrupts redox balance and leads to adverse effects, including cell apoptosis, proliferation inhibition, and functional impairment

The pathophysiological mechanism activates local inflammation, which is a barrier to allograft long-term immune tolerance

Perez-Escuredo et al., 2016

Despite these numerous advantages, inhaled drug delivery encounters considerable barriers that limit its overall effectiveness 13,114 (Fig

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