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Phase 1 trial of MLN0128 (Sapanisertib) and CB-839 HCl (Telaglenastat) in patients with advanced NSCLC (NCI 10327): rationale and study design

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Hyperexcitability in MS Although synaptic alterations and neuronal hyperexcitability have not been as extensively studied in MS as in the case of AD, these factors are increasingly being proposed as key points in the early degeneration that occurs in this disease