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In experimental models, Abdul Wanees El-Awdan et al

Proc Natl Acad Sci U S A (2018) 115:928893

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GHRH (0.3 micrograms/kg body wt) was given in early sleep [i.e., 1st slow-wave (SW) period], late sleep (i.e., 3rd REM period), and early sleep after sleep deprivation until 0400 h (i.e., 1st SW period)

Additionally, it promotes normal immunological performance