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If you are on a higher dose of metformin, divide it up and take a smaller amount with multiple meals instead of all at once

N., Amaral-Machado, L., & Egito, E

New Engl J Med 362:779-89

Data analysis Microsoft Excel 2016 software was used to collate data

J Photochem Photobiol, B 3:465

Another recent screening identified that H3K9 demethylation-mediated upregulation of BCAT1 and subsequent BCAA metabolic reprogramming is able to enhance the capacity for sublethal epidermal growth factor receptor (EGFR) inhibitor (TKI) resistance by producing ROS scavengers in lung cancer, which is a cancer where EGFR mutations are commonly found (Wang et al., 2019b)