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Navigating the aftermath of a traumatic brain injury (TBI) can be a profoundly challenging journey, not only for the survivors but also for their loved ones

In preclinical heart failure models, NNMT enzyme inhibition markedly reduced cardiac 1-MNA (by 77.1%), improved cardiac function, reduced left ventricular hypertrophy and fibrosis, and decreased pro-inflammatory gene expression

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In patients with hypersensitivity to the drug, seizures, agitation, paresthesia, tremors, and euphoria may occur

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Harkonen & Kjellstrand, 1979