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[DOI] [PMC free article] [PubMed] [Google Scholar] 89.Tsurusaki S., Tsuchiya Y., Koumura T., Nakasone M., Sakamoto T., Matsuoka M., Imai H., Yuet-Yin Kok C., Okochi H., Nakano H., et al

In addition, bivalent inhibitors of GSTs are able to bind to both active sites and interact with both junction and cleft regions of the enzyme, thus showing even higher affinity and better isozyme selectivity compared to monovalent inhibitors [203]

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Ichikawa T, Horie-Inoue K, Ikeda K, Blumberg B, Inoue S

doi: 10.2174/157015910792246244