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Patients should maintain adequate fluid intake based on individual needs, with the goal of maintaining pale yellow urine color

The influence of MTHFR on psychiatric diseases is mainly through reduction of MTHFR activity which results in elevation of homocysteine, reduction of DNA methylation-dependent methyl donor, finally induces hypomethylation, and then active disease-related genes

Unlike many nutrients, B12 is produced exclusively by bacteria and obtained primarily through animal-based foods including meat, fish, eggs, and dairy products

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But a better choice is combining adenosylcobalamin and hydroxocobalamin, a precursor of vitamin B12 that benefits the myelin nerve sheath and supports mitochondrial health